I had a customer who used Acu4GL for SYBASE with the old version for a long time, but sometimes the application got MAV error. Because the older veriosn was just for 32-bit Windows, and the customer is using the current Windows platforms which almost are Windows x64, we apply an evaluation of version 10.5 to test for the newer Windows x64 platforms. According the content in the document, Acu4GL for SYBASE can use  the 32-bit libraries with a 64-bit runtime and 32-bit Acu4GL for Sybase. So we just installed the 64-bit version which included runtime  and Acu4GL for SYBASE 32-bit (can choose from the product selections). But after some initial procedures working(like new stored procedures creation), we found the application seemed didn't direct the file I/O through Acu4GL for SYBASE(no SQL statements in the log file) and just got file error 35.

Does anyone know how to set up the Winodws environment for v10.5 x64 version to let Acu4GL for SYBASE work?

SYBASE was 12.5 and the client libraries were 32-bit. We just applied Windows x64 platform evaluation, and got the runtime & Acu4GL for SYBASE licenses for Windows x64.