ZENworks Patch Management now supports the deployment of Microsoft Office 365 updates (starting with Office 365 2016) from the Current Channel, Deferred Channel, and First Release for Deferred Channel. Patches for each of these channels can be seen in the Patches list in ZENworks Control Center.
With most Windows patches, ZENworks Patch Management orchestrates the entire patch process, including delivering the patches to the devices. With Office 365 updates, however, ZENworks Patch Management leaves the patch delivery to Office 365. This means that:
It's pretty simple -- let ZENworks Patch Management manage the update process and let Office 365 manage the content delivery.
As always, I encourage you to set up a Patch policy to automate the deployment of your Office 365 updates. Here is what I did in my system: