Any changes with SImple MAPI in 10.1

We upgraded from 9.4 to 10.1 and since then our email option has stopped working.  We use GMail as our mail client and use a third party application called Affixa.  This uses SImple MAPI to attach a cm10 doc to a draft email in the GMail client.  Its now defaulting to Outlook.  Are there any other global settings I should investigate?

Thanks

DBB