Data Protector should support Global Excludes of files/folders with and without wildcards for a single or multiple backup specs. Using templates (apply Tree) is not what we need, since it needs to be re-applied when changes have been done.
Existing Enhancement Requests:
QCCR2A61924: Request to add to Cell Manager Global Exclude List of Files/Folders with wildcards
OCTCR19Q330241: Request to add a Global Exclude List of Files/Folders
Improve exclude managed for File and Folders for environments in scale out environments with multiple servers having access to the same shared data and clients are added on a regular basis.