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MFDC 12.1 and Windows 10 1803 problems

There seems to be a lot of problems with Desktop Container applications in Windows 10 1803

Studio does not open, instead I get an error message: - .NET Framework Initialization Error
Please set registry key HKLM\Software\Microsoft\.NETFramework\InstallRoot to point to the .NET Framework install location

The registry key seems ok (in x64 and x86 registry)

The majority of our virtual applications doesn't start at all (various errors)

I tested the latest version of Studio and it works so I hope Micro Focus release an updated version of Desktop Containers Studio soon... maybe someone knows when?