New OO Installation vs Upgrading

I am looking at upgrading all the way from 10.22 to 10.80.  I am concerned with possible incompatabilities with existing content packs as part of the upgrade.  Also possible extended outages if we have to revert the upgrade due to unforeseen issues.  I am wondering if it would be easier to just stand up a new instance of 10.80 and move our content packs over (testing as we migrate) instead of upgrading the existing instance.

Does anyone have any experience/insight for a multi-version upgrade like this?

Thanks,

Mike R