Studio debugger problem since update

Yesterday we upgraded OO from 10.80 to 2019.07.

Since the update we have a frequent issue with studio Debugging against Central.

It can be working fine then Intermittently when running the debugger we are get an error message "An error has occured during your run"

org.springframework.remoting.RemoteAccessException: Could not access HTTP invoker remote service at [https://ooprod:8443/oo/central-remoting/workerNodeService]; nested exception is org.apache.http.NoHttpResponseException: Did not receive successful HTTP response: status code = 401, status message = [Unauthorized]

Then if you restart studio it works fine again. Then a little while later when you try again the error occurs and you have to restart Studio