JMX Monitor Problems
Based on that information, even though the monitors have been configured on intervals and you made Sizing on the server, one of the reason could be related that in a specific moment the a peak of monitor could be running at same time.
Let me know something, are you using Domain filter on that monitors?
SW Support Engineer
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Make your connection pool per Key is not exhausted, check SiteScope help for minimum evictable idle time recommendation and for other JMX monitor Limitations.
“If you find this or any post resolves your issue, please be sure to mark it as an accepted solution.”